Genes That Bias Mendelian Segregation
نویسندگان
چکیده
منابع مشابه
Genes That Bias Mendelian Segregation
Mendel laws of inheritance can be cheated by Meiotic Drive Elements (MDs), complex nuclear genetic loci found in various eukaryotic genomes and distorting segregation in their favor. Here, we identify and characterize in the model fungus Podospora anserina Spok1 and Spok2, two MDs known as Spore Killers. We show that they are related genes with both spore-killing distorter and spore-protecting ...
متن کاملWhy Mendelian segregation?
The discovery of alleles that are able to distort segregation during meiosis in their favour raises the question of why Mendelian segregation is the rule and segregation distortion the exception. Previous research on this topic was limited by an unrealistic assumption: equal segregation in the two sexes. Ubeda and Haig [(2005) Genetics 170, 1345-1357] provide a new model allowing sex-specific s...
متن کاملOn the evolutionary stability of Mendelian segregation.
We present a model of a primary locus subject to viability selection and an unlinked locus that causes sex-specific modification of the segregation ratio at the primary locus. If there is a balanced polymorphism at the primary locus, a population undergoing Mendelian segregation can be invaded by modifier alleles that cause sex-specific biases in the segregation ratio. Even though this effect i...
متن کاملSpindle asymmetry drives non-Mendelian chromosome segregation.
Genetic elements compete for transmission through meiosis, when haploid gametes are created from a diploid parent. Selfish elements can enhance their transmission through a process known as meiotic drive. In female meiosis, selfish elements drive by preferentially attaching to the egg side of the spindle. This implies some asymmetry between the two sides of the spindle, but the molecular mechan...
متن کاملHas Income Segregation Really Increased? Bias and Bias Correction in Sample-Based Segregation Estimates
Several recent studies have concluded that residential segregation by income in the U.S. has increased in the decades since 1970, including a significant increase after 2000. Income segregation measures, however, are biased upwards when based on sample data. This is a potential concern because the sampling rate of the American Community Survey (ACS)—from which post-2000 income segregation estim...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2014
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1004387